Kolegij
Studiji
Medical Studies in EnglishStudijska godina
2ISVU ID
188675ECTS
1.5
The aim of the course is to familiarize students with the pathological function of the immune system through the presentation of clinical cases. The emphasis is on explaining the pathophysiological mechanisms that lead to the disruption of normal immune processes, as well as on the possibilities of therapeutic actions on the immune reaction. The tasks of the class are to enable the student to connect basic knowledge in immunology and the pathophysiology of the immune system with nosological entities found in clinical medicine. The course includes the following entities: X-linked agammaglobulinemia, Congenital asplenia, MHC class I deficiency, X-linked severe combined immunodeficiency, Toxic shock syndrome, Hereditary angioneurotic edema, Graft-versus-host reaction, AIDS, Myasthenia gravis, Allergic asthma, Multiple sclerosis, Rheumatic fever
Rosen F., Geha R. and Notarangelo L.: Case Studies in Immunology: a clinical companion 7th edition, Garland science, 2016.
Classes are conducted in the form of seminars. At the seminars, the student actively discusses pathophysiological immune mechanisms with the teacher. Student obligations include regular attendance at seminars. The student is obliged to prepare the material that is discussed in class.
Regular attendance of classes.
The aim of the course is to familiarize students with the pathological function of the immune system through the presentation of clinical cases. The emphasis is on explaining the pathophysiological mechanisms that lead to the disruption of normal immune processes, as well as on the possibilities of therapeutic actions on the immune reaction. The tasks of the class are to enable the student to connect basic knowledge in immunology and the pathophysiology of the immune system with nosological entities found in clinical medicine. The course includes the following entities: X-linked agammaglobulinemia, Congenital asplenia, MHC class I deficiency, X-linked severe combined immunodeficiency, Toxic shock syndrome, Hereditary angioneurotic edema, Graft-versus-host reaction, AIDS, Myasthenia gravis, Allergic asthma, Multiple sclerosis, Rheumatic fever
Rosen F., Geha R. and Notarangelo L.: Case Studies in Immunology: a clinical companion 7th edition, Garland science, 2016.
Classes are conducted in the form of seminars. At the seminars, the student actively discusses pathophysiological immune mechanisms with the teacher. Student obligations include regular attendance at seminars. The student is obliged to prepare the material that is discussed in class.
Regular attendance of classes.
The aim of the course is to familiarize students with the pathological function of the immune system through the presentation of clinical cases. The emphasis is on explaining the pathophysiological mechanisms that lead to the disruption of normal immune processes, as well as on the possibilities of therapeutic actions on the immune reaction. The tasks of the class are to enable the student to connect basic knowledge in immunology and the pathophysiology of the immune system with nosological entities found in clinical medicine. The course includes the following entities: X-linked agammaglobulinemia, Congenital asplenia, MHC class I deficiency, X-linked severe combined immunodeficiency, Toxic shock syndrome, Hereditary angioneurotic edema, Graft-versus-host reaction, AIDS, Myasthenia gravis, Allergic asthma, Multiple sclerosis, Rheumatic fever
Rosen F., Geha R. and Notarangelo L.: Case Studies in Immunology: a clinical companion 7th edition, Garland science, 2016.
Classes are conducted in the form of seminars. At the seminars, the student actively discusses pathophysiological immune mechanisms with the teacher. Student obligations include regular attendance at seminars. The student is obliged to prepare the material that is discussed in class.
Regular attendance of classes.
The aim of the course is to familiarize students with the pathological function of the immune system through the presentation of clinical cases. The emphasis is on explaining the pathophysiological mechanisms that lead to the disruption of normal immune processes, as well as on the possibilities of therapeutic actions on the immune reaction. The tasks of the class are to enable the student to connect basic knowledge in immunology and the pathophysiology of the immune system with nosological entities found in clinical medicine. The course includes the following entities: X-linked agammaglobulinemia, Congenital asplenia, MHC class I deficiency, X-linked severe combined immunodeficiency, Toxic shock syndrome, Hereditary angioneurotic edema, Graft-versus-host reaction, AIDS, Myasthenia gravis, Allergic asthma, Multiple sclerosis, Rheumatic fever
Rosen F., Geha R. and Notarangelo L.: Case Studies in Immunology: a clinical companion 7th edition, Garland science, 2016.
Classes are conducted in the form of seminars. At the seminars, the student actively discusses pathophysiological immune mechanisms with the teacher. Student obligations include regular attendance at seminars. The student is obliged to prepare the material that is discussed in class.
Regular attendance of classes.
Ishodi učenja
- To explain the processes of normal B-cell maturation, and the effector functions of antibodies.
- To explain the consequences of the B lymphocytes' primary maturation disorders and the disorders in humoral-specific immunity t.
- To explain the role of the spleen in immunity and the immunological and clinical consequences of its deficiency
Ishodi učenja
- To describe the features of the gene organization of the MHC system and the endogenous pathway of antigen presentation.
- To describe the development of cytotoxic T lymphocytes in the thymus on MHC class I molecules, and the clinical disorders that arise due to the inability of these cells to mature.
- To explain the processes of primary maturation of T lymphocytes, the causes of the absence of their production and the clinical features of disorders that arise as a result
Ishodi učenja
- To describe the structure and genetic organization of the T-lymphocyte receptor, as well as the properties of T-cell activation and the role of superantigens.
- To describe the features of macrophage activation by cytokines, and the clinical manifestations of toxic shock.
- To explain the features of the classical and alternative pathways of complement activation.
- To describe the clinical consequences of serine protease inhibitor deficiency (inhibitor of activation of the complement component C1) in the pathogenesis of hereditary angioneurotic edema.
Ishodi učenja
- To describe the processes of T-lymphocyte recognition of foreign MHC molecules, and the characteristics of bone marrow transplantation.
- To explain pathogenetic mechanisms and clinical features of transplantation disease.
- To describe the features of HIV infection and immune control of HIV infection. Describe the features of the pathogenesis of HIV disease and the consequences of insufficient cellular and humoral immunity
Ishodi učenja
- To describe the mechanisms of the immune tolerance of self and the development of humoral autoimmune disorders.
- To describe the pathogenesis and clinical features of myasthenia gravis.
- To describe the mechanisms of IgE-mediated hypersensitivity.
- To describe the pathogenesis and clinical signs of allergic asthma, and skin hypersensitivity prick test.
Ishodi učenja
- To describe the mechanisms of development of central and peripheral tolerance.
- To describe the development of autoimmune mechanisms in cellular immunity and clinical signs and symptoms of multiple sclerosis.
- To describe the consequences of the Rh incompatibility between mother and fetus.
- To explain the pathogenesis and clinical features of the fetal erythroblastosis.
Ishodi učenja
- To explain the processes of normal B-cell maturation, and the effector functions of antibodies.
- To explain the consequences of the B lymphocytes' primary maturation disorders and the disorders in humoral-specific immunity t.
- To explain the role of the spleen in immunity and the immunological and clinical consequences of its deficiency
Ishodi učenja
- To describe the features of the gene organization of the MHC system and the endogenous pathway of antigen presentation.
- To describe the development of cytotoxic T lymphocytes in the thymus on MHC class I molecules, and the clinical disorders that arise due to the inability of these cells to mature.
- To explain the processes of primary maturation of T lymphocytes, the causes of the absence of their production and the clinical features of disorders that arise as a result
Ishodi učenja
- To describe the structure and genetic organization of the T-lymphocyte receptor, as well as the properties of T-cell activation and the role of superantigens.
- To describe the features of macrophage activation by cytokines, and the clinical manifestations of toxic shock.
- To explain the features of the classical and alternative pathways of complement activation.
- To describe the clinical consequences of serine protease inhibitor deficiency (inhibitor of activation of the complement component C1) in the pathogenesis of hereditary angioneurotic edema.
Ishodi učenja
- To describe the processes of T-lymphocyte recognition of foreign MHC molecules, and the characteristics of bone marrow transplantation.
- To explain pathogenetic mechanisms and clinical features of transplantation disease.
- To describe the features of HIV infection and immune control of HIV infection. Describe the features of the pathogenesis of HIV disease and the consequences of insufficient cellular and humoral immunity
Ishodi učenja
- To describe the mechanisms of the immune tolerance of self and the development of humoral autoimmune disorders.
- To describe the pathogenesis and clinical features of myasthenia gravis.
- To describe the mechanisms of IgE-mediated hypersensitivity.
- To describe the pathogenesis and clinical signs of allergic asthma, and skin hypersensitivity prick test.
Ishodi učenja
- To describe the mechanisms of development of central and peripheral tolerance.
- To describe the development of autoimmune mechanisms in cellular immunity and clinical signs and symptoms of multiple sclerosis.
- To describe the consequences of the Rh incompatibility between mother and fetus.
- To explain the pathogenesis and clinical features of the fetal erythroblastosis.