The aim of the course is to acquaint students with the most diverse forms of drug-induced rashes, including those that are rare but severe and life-threatening, as well as those that are more frequent, which every doctor encounters in his clinical practice, regardless of a specialist orientation.

A further goal is to acquaint students with reactions to new classes of drugs, including biological drugs (such as TNF antagonists, and other anti-cytokines which are increasingly being used in the treatment of numerous inflammatory diseases in rheumatology, clinical immunology, gastroenterology and dermatology) and new oncological drugs (targeted therapy and tumor immunotherapy).

Course content:

• etiology and mechanisms of side effects to drugs (immunological and non-immunological, idiosyncratic)
• maculopapular exanthem, urticaria and angioedema, erythema multiforme, fixed erythema, baboon syndrome, annular erythema
• acneiform, psoriasiform and lichenoid rashes, drug-induced lupus, vasculitis, pemphigus and pemphigoid
• photosensitivity, hair and nail changes, pigmentation disorders
• life-threatening drug reactions: Stevens Johnson syndrome, toxic epidermal necrolysis, systemic drug hypersensitivity syndrome (DRESS/DIHS), acute generalized exanthematous pustulosis
• skin reactions to radiocontrast agents
• skin side effects of biological drugs (tumor necrosis factor antagonists and others)
• skin side effects of traditional and new oncology drugs (epidermal growth factor receptor antagonists, BRAF inhibitors, multikinase inhibitors, mTOR inhibitors, PD-1 antagonists)