Kolegij
Studiji
Medical Studies in EnglishStudijska godina
2ISVU ID
201394ECTS
1.5
Free radicals as extremely reactive chemical species represent a potential danger to all cells and contribute to the development of cardiovascular, neurodegenerative and inflammatory diseases, tumors, diabetes and other pathological conditions. However, at the same time, free radicals and other reactive oxygen and nitrogen species (ROS, "reactive oxygen species", RNS, "reactive nitrogen species"), by participating in phagocytosis and oxygenation, have a significant positive effect on metabolism. Within the framework of the course, the modes of action and effects of free radicals and ROS and RNS molecules in oxidative stress and the pathogenesis of various diseases will be discussed. In addition, students will be able to explain how the organism is protected from their harmful effects.
1. Selected scientific papers.
1. Internet databases.
Attendance and active participation of students in classes. The student must, in agreement with the course leader, prepare a seminar paper and make a PowerPoint presentation from a specific area related to oxidative stress. Students present their PowerPoint presentations in front of the leader and other colleagues. Every student is obliged to submit his seminar paper and PowerPoint presentation in electronic form.
Student evaluation is carried out according to the valid Rulebook on studies of the University of Rijeka and according to the Rulebook on student evaluation at the Faculty of Medicine in Rijeka.
Free radicals as extremely reactive chemical species represent a potential danger to all cells and contribute to the development of cardiovascular, neurodegenerative and inflammatory diseases, tumors, diabetes and other pathological conditions. However, at the same time, free radicals and other reactive oxygen and nitrogen species (ROS, "reactive oxygen species", RNS, "reactive nitrogen species"), by participating in phagocytosis and oxygenation, have a significant positive effect on metabolism. Within the framework of the course, the modes of action and effects of free radicals and ROS and RNS molecules in oxidative stress and the pathogenesis of various diseases will be discussed. In addition, students will be able to explain how the organism is protected from their harmful effects.
1. Selected scientific papers.
1. Internet databases.
Attendance and active participation of students in classes. The student must, in agreement with the course leader, prepare a seminar paper and make a PowerPoint presentation from a specific area related to oxidative stress. Students present their PowerPoint presentations in front of the leader and other colleagues. Every student is obliged to submit his seminar paper and PowerPoint presentation in electronic form.
Student evaluation is carried out according to the valid Rulebook on studies of the University of Rijeka and according to the Rulebook on student evaluation at the Faculty of Medicine in Rijeka.
Free radicals as extremely reactive chemical species represent a potential danger to all cells and contribute to the development of cardiovascular, neurodegenerative and inflammatory diseases, tumors, diabetes and other pathological conditions. However, at the same time, free radicals and other reactive oxygen and nitrogen species (ROS, "reactive oxygen species", RNS, "reactive nitrogen species"), by participating in phagocytosis and oxygenation, have a significant positive effect on metabolism. Within the framework of the course, the modes of action and effects of free radicals and ROS and RNS molecules in oxidative stress and the pathogenesis of various diseases will be discussed. In addition, students will be able to explain how the organism is protected from their harmful effects.
1. Selected scientific papers.
1. Internet databases.
Attendance and active participation of students in classes. The student must, in agreement with the course leader, prepare a seminar paper and make a PowerPoint presentation from a specific area related to oxidative stress. Students present their PowerPoint presentations in front of the leader and other colleagues. Every student is obliged to submit his seminar paper and PowerPoint presentation in electronic form.
Student evaluation is carried out according to the valid Rulebook on studies of the University of Rijeka and according to the Rulebook on student evaluation at the Faculty of Medicine in Rijeka.
Free radicals as extremely reactive chemical species represent a potential danger to all cells and contribute to the development of cardiovascular, neurodegenerative and inflammatory diseases, tumors, diabetes and other pathological conditions. However, at the same time, free radicals and other reactive oxygen and nitrogen species (ROS, "reactive oxygen species", RNS, "reactive nitrogen species"), by participating in phagocytosis and oxygenation, have a significant positive effect on metabolism. Within the framework of the course, the modes of action and effects of free radicals and ROS and RNS molecules in oxidative stress and the pathogenesis of various diseases will be discussed. In addition, students will be able to explain how the organism is protected from their harmful effects.
1. Selected scientific papers.
1. Internet databases.
Attendance and active participation of students in classes. The student must, in agreement with the course leader, prepare a seminar paper and make a PowerPoint presentation from a specific area related to oxidative stress. Students present their PowerPoint presentations in front of the leader and other colleagues. Every student is obliged to submit his seminar paper and PowerPoint presentation in electronic form.
Student evaluation is carried out according to the valid Rulebook on studies of the University of Rijeka and according to the Rulebook on student evaluation at the Faculty of Medicine in Rijeka.
Ishodi učenja
Objasniti što je oksidacijski stres. Opisati slobodne radikale, reaktivne spojeve kisika i dušika, prooksidanse i antioksidanse. Istaknuti važnost pravilne prehrane. Protumačiti stvaranje reaktivnih spojeva kisika i dušika. Navesti način i mjesta stvaranja slobodnih radikala i drugih reaktivnih spojeva u metabolizmu.
Ishodi učenja
Protumačiti fiziološku funkciju reaktivnih spojeva kisika i dušika. Objasniti ulogu slobodnih radikala i drugih reaktivnih spojeva u metabolizmu.
Ishodi učenja
Navesti koji su biljezi oksidacijskog oštećenja DNA. Objasniti produkte nastale u reakciji slobodnih radikala s DNA i metode njihovog određivanja. Navesti koji su biljezi oksidacijskog oštećenja proteina. Objasniti produkte nastale u reakciji slobodnih radikala s proteinima i metode njihovog određivanja. Navesti koji su biljezi oksidacijskog oštećenja lipida. Objasniti produkte nastale u reakciji slobodnih radikala s lipidima i metode njihovog određivanja.
Ishodi učenja
Navesti enzimske antioksidanse. Objasniti ulogu superoksid dismutaze, glutation peroksidaze i katalaze u redukciji oksidacijskog oštećenja stanice. Navesti neenzimske antioksidanse. Objasniti ulogu vitamina C, vitamina E, karotenoida, glutationa, melatonina, liponskae kiseline, flavonoida i dr. spojeva s antioksidacijskim učinkom u sprječavanju oksidacijskog oštećenja stanice.
Ishodi učenja
Povezati reaktivnr spojevr kisika i dušika, starenje i patološka stanja. Protumačiti ulogu slobodnih radikala i drugih reaktivnih spojeva u procesu starenja, razvoju dijabetesa, kardiovaskularnih bolesti, tumora i drugih kroničnih bolesti.
Ishodi učenja
Objasniti što je oksidacijski stres. Opisati slobodne radikale, reaktivne spojeve kisika i dušika, prooksidanse i antioksidanse. Istaknuti važnost pravilne prehrane. Protumačiti stvaranje reaktivnih spojeva kisika i dušika. Navesti način i mjesta stvaranja slobodnih radikala i drugih reaktivnih spojeva u metabolizmu.
Ishodi učenja
Protumačiti fiziološku funkciju reaktivnih spojeva kisika i dušika. Objasniti ulogu slobodnih radikala i drugih reaktivnih spojeva u metabolizmu.
Ishodi učenja
Navesti koji su biljezi oksidacijskog oštećenja DNA. Objasniti produkte nastale u reakciji slobodnih radikala s DNA i metode njihovog određivanja. Navesti koji su biljezi oksidacijskog oštećenja proteina. Objasniti produkte nastale u reakciji slobodnih radikala s proteinima i metode njihovog određivanja. Navesti koji su biljezi oksidacijskog oštećenja lipida. Objasniti produkte nastale u reakciji slobodnih radikala s lipidima i metode njihovog određivanja.
Ishodi učenja
Navesti enzimske antioksidanse. Objasniti ulogu superoksid dismutaze, glutation peroksidaze i katalaze u redukciji oksidacijskog oštećenja stanice. Navesti neenzimske antioksidanse. Objasniti ulogu vitamina C, vitamina E, karotenoida, glutationa, melatonina, liponskae kiseline, flavonoida i dr. spojeva s antioksidacijskim učinkom u sprječavanju oksidacijskog oštećenja stanice.
Ishodi učenja
Povezati reaktivnr spojevr kisika i dušika, starenje i patološka stanja. Protumačiti ulogu slobodnih radikala i drugih reaktivnih spojeva u procesu starenja, razvoju dijabetesa, kardiovaskularnih bolesti, tumora i drugih kroničnih bolesti.