Kolegij
Studiji
Medical Studies in EnglishStudijska godina
4ISVU ID
213825ECTS
2.00
The course of Clinical Oncology is a mandatory course at the fourth year of Medical school, which consists of 15 lectures as well as 15 practical teachings, 30 in total (2.0 ECTS). Lectures will be held in a lecture hall at the Clinic in the Hospital of Rijeka,while the practical part will be demonstrated at the Department of Oncology and Radiotherapy, Hospital of Rijeka.
The aim of this course is to introduce the medical students to the basics of origin of malignant diseases, main factors that cause it, cures and treatment as well as side effects.Another aim of this course is to incorporate knowledge on how to care about a terminally ill patient, and basic palliative care. Introducing the students to the measures of preventive treatments.
Syllabus: Students are taught about the biology of tumor growth and risk factors that can lead to malignant diseases.We shall be discussing the most common tumors and we will talk about each one as well as the basic therapy for a specific tumor. We shall be looking into the cytostatic treatment, radiotherapy (radical and palliative), biological therapy and hormonal therapy.Side effects of both oncological therapy,chemotherapy as well as radiotherapy will be looked into. We will also talk about palliative care and things that are done regarding palliative care. Prevention programmes in Croatia are also on the agenda.
Expected learning outcomes:
- Explain the molecular genetic basis of cancer
- Explain the way the immune system recognizes and fight malignant cells
- Explain findings on metastasis and angiogenesis
- Indicate the incidence and mortality of cancer in the country and the world
- List the basic risk factors for cancer
- Explain ways to prevent disease
- List and explain the basic therapy metods in oncology : radiotherapy, chemotherapy , biological therapy, immunotherapy, hormone therapy, and less applayed forms of treatments
- List the incidence of the disease and factor of risks , therapy possibilities , prognostic parameteres, prevention methods
Lectures will consist of both, theoretical and practical classes. Estimated course duration is 4 weeks time. After taking the final exam the student will be awarded with 2.0 ECTS points.
DeVita H. et al.: Principles and Practice of Oncology, 11th Edition, Lippincott, Williams & Wilkins, 2018
Students must attend lessons regularly and be actively involved in all the aspects of the course.During lessons and practical part, they must be ready at all times to answer questions. Therefore students must read designated texts before class and be prepared to participate in the lessons. The students must take two exames (2 half exames and the final exam).Students can be absent from the maximum of 30% of the classes, exclusively due to health reasons confirmed by a GP. Being present at classes is mandatory.The compensation of the lost classes is possible only with the agreement by the lecturer. In case the student is absent for more than 30% of the classes, it shall lose the privilege to attend further classes and to take the final exam. In accordance with that, the student has gained 0 ECTS points and is graded F.
Grading criteria is carried out according to valid Regulations of studies University of Rijeka, and according to Regulations of grading students at the Faculty of Medicine in Rijeka (adopted by the Faculty committee of Medicine in Rijeka).
Final grade- written exam (max 50% of the final grade) + final oral exam (max of 50% of the final grade)
Written examination consists of 50 questions and can amount to max 50% of the final grade. Due to the results of the written part, the student qualifies to take the final oral exam. Students that get >25%, in the written part (25 or more correctly answered questions), get the right to take the final oral examination.
Final exam is oral and the student can get a maximum of 50% of the final grade, and depending on the satisfactory results of the exam it gets 25 or more percent according to the final grade.
- 45-50% excellent (5)- (A)
- 35-44 % very good (4)- (B)
- 30-34% good (3)- (C)
- 25-29% sufficient (2)- (D)
Final grade: written examination + final oral exam
- 90-100% 5 A Excellent
- 75-89,9% 4 B Very good
- 60-74,9% 3 C Good
- 50-59,9% 2 D Sufficient
- 0-49,9% 1 F Insufficient
Classes, as well as all the other information about the course, such as exam dates are to be found on line, Department of Oncology and Radiotherapy
Ishodi učenja
Understanding the basics of the scope of oncology multidisciplinary science as well as ways of recognizing and evaluating an oncology patient and the basics of treatment in oncology. Basic concepts in diagnostics, treatment and epidemiology.
Ishodi učenja
Basics of tumor biology, carcinogenesis, angiogenesis and metastasis. Getting to know the molecular-genetic basis of cancer and what knowledge we use for the targeted treatment of malignant tumors. Basic knowledge of cell division and cell metabolism that we use in current and future ways of treating malignant diseases. Mechanisms of immunological recognition of malignant cells, tumor microcysts and the relationship with the host, the way of evolution, heterogeneity, metastases, angiogenesis and other mechanisms in tumor treatment and the fight against tumors. Through all these mechanisms, modern technologies, which are partly already applied and will follow in the further development of diagnostics and treatment of malignant diseases.
Ishodi učenja
Principles of cytostatic therapy, hormone therapy, biotherapy and other types of therapy)
Acquaintance of students with multimodal methods of tumor treatment, surgery, cytostatics, hormone therapy and other methods.
Ishodi učenja
Understanding progressive therapies that are rapidly developing in the world. The ways in which they work, which are further directions for improving the success of the treatment.
Ishodi učenja
Getting to know the physical basics of radiation. Understanding of radiotherapy devices, effectiveness and side effects.
Ishodi učenja
Acquaintance of students with risk factors for breast cancer. Histological and phenotypic differences in the behavior and treatment of breast cancer, multimodal principles of treatment and monitoring. Primary and secondary prevention.
Ishodi učenja
Acquaintance of students with risk factors for malignant tumors of the female sexual organs. Histological and phenotypic differences in the behavior and treatment, multimodal principles of treatment and monitoring. Primary and secondary prevention.
Ishodi učenja
Acquaintance of students with risk factors for malignant tumors of the respiratory system and mediastinum. Histological and phenotypic differences in the behavior and treatment, multimodal principles of treatment and monitoring. Primary and secondary prevention.
Ishodi učenja
Risk factors in both the female and male reproductive system. Most common pathohistological types.Methods of spreading of aforementioned tumors. Treatment of malignant tumors: surgically, with cytostatics, with radiotherapy, with biological therapy and with hormonal therapy. Prevention measures.
Ishodi učenja
Risk factors for the malignant tumors of the urinary system and male sexual organs. Most common pathohistological types. Methods of spreading of aforementioned tumors. Treatment of malignant tumors: surgically, with cytostatics, with radiotherapy and with biological therapy. Prevention measures.
Ishodi učenja
Risk factors for malignant tumors of the digestive and urinary tract system.Most common pathohistological types. Methods of spreading of aforementioned tumors. Treatment of malignant tumors: surgically, with cytostatics,with radiotherapy, and with biological therapy. Prevention measures.
Ishodi učenja
Risk factors for malignant bone and soft tissue tumors, and common pathohistological types. Methods of spreading of aforementioned tumors. Treatment of malignant tumors: surgically, with cytostatics, with radiotherapy, and with biological therapy. Prevention measures.
Ishodi učenja
Risk factors for the malignant tumors of the hematopoietic, lymphatic and endocrine systems. Most common pathohistological types. Methods of spreading of aforementioned tumors. Treatment of malignant tumors: with cytostatics, with radiotherapy and with biological therapy. Prevention measures.
Ishodi učenja
Risk factors for the malignant skin tumors and of central nervous system. Most common pathohistological types. Methods of spreading of aforementioned tumors. Treatment of malignant tumors: surgically, with cytostatics, with radiotherapy and with biological therapy. Prevention measures.
Ishodi učenja
Introducing students to patients in poor general condition and different ways of how to take care of them. Introducing palliative radiotherapy and chemotherapy. All the measures of symptomatic therapy.Introducing dietary issues and analgesic therapy. Pain infirmary. How does a hospice function? How are these patients supported by the system?
Ishodi učenja
Mastering the approach to the oncological patient, taking of the anamnesis and status.
Ishodi učenja
Introduction to the radiation devices and their effect on the tissue. Side effects of the radiation and the recovery. Introduction to cytostatic therapy at the departments as well as at the day clinic. Administration of cytostatics, side effects and recovery. How to take care of febrile neutropenia. Introduction to the biological therapy, administration, side effects and recovery.
Ishodi učenja
Introducing students to breast-conserving and radical surgery performed on female patients. Anamnesis and status. Plan of the radiotherapy. Side effects and remedy of radiation. Administration of cytostatics. Premedication. Side effects and recovery of cytostatics. Exercise of rights to a wig or breast prosthetics.Lymph drainage.
Ishodi učenja
Cases of female patients with vaginal, vulva, uterus and ovaries tumors. Anamnesis and status.Brachytherapy- simulation of the application of radioactive caesium. Side effects and recovery.
Ishodi učenja
Cases of patients with prostate tumors, localized illness and with metastazis. Anamnesis and status.Planning of conformal radiotherapy. Hormonal radiotherapy. Application of LHRH agonist. Radiation of bone metastasis. Cytostatic therapy in curing the prostate cancer.
Ishodi učenja
Cases of patients with intratoracal tumors: lungs tumors and mesotheliomas. Anamnesis and status. Planning of radical radiotherapy.Cytostatic and biological therapy. Getting the patient ready for the administration of cytostatics. Syndrome of vena cava and Pancoast syndrome, treated as emergencies in oncology.
Ishodi učenja
Cases of patients with esophagus, stomach, pancreas and colorectal tumors. Radiation side effects and recovery. Cytostatic therapy for aforementioned tumors. Cytostatic side effects and recovery. Application of biological therapy. Anus praeter.
Ishodi učenja
Cases of patients with urinary bladder cancer and malignant kidneys tumors. Anamneses and status.Planning of radiotherapy concerning the urinary bladder cancer, immunotherapy. Biological therapy and its side effects. Recovery. Urostoma, nefrostoma.
Ishodi učenja
Cases of patients with oral cavity, pharynx and larynx tumors. Anamnesis and status.Planning of concomitant chemoradiotherapy for the aforementioned tumors. Side effects and recovery from radiation and cytostatic therapy.
Ishodi učenja
Cases of patients with malignant tumors of the central nervous system and paranasal sinuses. Anamnesis and status. Planning of radiotherapy for the glioblastoma and maxilla cancer. Therapy of the brain edema. Cytostatic therapy. Spinal cord compression. Supportive methods.
Ishodi učenja
Cases of patients with testicular tumor of seminoma and nonseminoma type. Anamnesis and status.Radiotherapy and cytostatic therapy. Side effects and recovery. Cryopreservation of sperm.
Ishodi učenja
Cases of basal cell carcinoma and planocellular skin carcinoma. Anamnesis and status.Radiotherapy. Treatment of radiodermatitis. Malignant melanoma. Treatment with special attention to biological therapy.
Ishodi učenja
Cases of bone and soft tissue tumors.Anamnesis and status. Treatment of sarcoma.
Ishodi učenja
Cases of hematological malignant diseases. Anamnesis and status, Radiation of the lymphoma and plasmacytoma.
Ishodi učenja
Cases of patients undertaking palliative treatment. Palliative patients’ diet. Gastrostomy PEG. Analgesic therapy. Pain clinic. Evacuation of ascites and pleural effusion.Palliative radiotherapy and chemotherapy.Teams for palliative care and hospices.
Ishodi učenja
Study outcome Introduction to the basic fields of oncological science as well as the methods of evaluation of the patient, and the basic treatment in oncology.
Ishodi učenja
Study outcome Introduction of the molecular-genetic basis of cancer which is becoming more and more the base for specific treatment of malign tumors. Revision of cell division, since the chemotherapy is based on the influence of cytostatics during individual phases of cell cycle.
Ishodi učenja
Study outcome Studying different methods of immune recognition of malignant cells, keeping in mind that the immunological system is one of the most important factors in the destroying of the malignant cells. Discussion on the causes of metastasis of malignant tumors,and about the creation of their own circulatory system. Introduction to the basics of molecular diagnostics which is becoming the basis in treatment with biological therapy.
Ishodi učenja
Study outcome How widespread are different types of malignant tumors throughout the world and in our country. What are the incidences of the most common types of tumor, in the world and in our country. Risk factors for some malign diseases. Measures of prevention for some malignant tumors.Getting to know some of the basic diagnostic methods in oncology.
Ishodi učenja
Study outcome Explaining to students the ways of surgical treatment of malignant tumors. Explaining to students the basic principles of oncology treatments: basis of cytostatic therapy, hormonal therapy, biotherapy and thermo phototherapy
Ishodi učenja
Study outcome Getting to know the basic physics of radiation. Getting to know the basic radiotherapy devices
Ishodi učenja
Study outcome How is tissue affected with radiation: normal and tumor tissue. Application of electrons and photons in radiotherapy.
Ishodi učenja
Study outcome Introducing the students to risk factors of breast cancer. Histology of breast cancer. Most common locations of the tumor. The ways of tumor spreading in the breasts. Methods of treating malign breast cancer: surgically, with cytostatics,with radiotherapy, biological therapy and hormonal therapy. Measures of prevention.
Ishodi učenja
Study outcome Risk factors in both the female and male reproductive system. Most common pathohistological types.Methods of spreading of aforementioned tumors. Treatment of malignant tumors: surgically, with cytostatics, with radiotherapy, with biological therapy and with hormonal therapy. Prevention measures.
Ishodi učenja
Study outcome Risk factors for the malign tumors of the respiratory system and mediastinum. Most common pathohistological types. Methods of spreading of aforementioned tumors. Treatment of malignant tumors: surgically, with cytostatics, with radiotherapy and with biological therapy. Prevention measures.
Ishodi učenja
Study outcome Risk factors for malignant tumors of the digestive and urinary tract system.Most common pathohistological types. Methods of spreading of aforementioned tumors. Treatment of malignant tumors: surgically, with cytostatics,with radiotherapy, and with biological therapy. Prevention measures.
Ishodi učenja
Study outcome Risk factors for malignant tumors of the head and neck, as well as of bones and soft tissues. Most common pathohistological types. Methods of spreading of aforementioned tumors. Treatment of malignant tumors: surgically, with cytostatics, with radiotherapy, and with biological therapy. Prevention measures.
Ishodi učenja
Study outcome Risk factors for the malignant tumors of the hematopoietic, lymphatic and endocrine systems. Most common pathohistological types. Methods of spreading of aforementioned tumors. Treatment of malignant tumors: with cytostatics, with radiotherapy and with biological therapy. Prevention measures.
Ishodi učenja
Study outcome
Risk factors for the malignant skin tumors and of the central nervous system.Most common pathohistological types. Methods of spreading of aforementioned tumors. Treatment of malignant tumors: surgically, with cytostatics, with radiotherapy and with biological therapy. Prevention measures.
Ishodi učenja
Study outcome
Introducing students to patients in poor general condition and different ways of how to take care of them. Introducing palliative radiotherapy and chemotherapy. All the measures of symptomatic therapy.Introducing dietary issues and analgesic therapy. Pain infirmary. How does a hospice function? How are these patients supported by the system?
Ishodi učenja
Study outcome
Mastering the approach to the oncological patient, taking of the anamnesis and status
Ishodi učenja
Study outcome: Introduction to the radiation devices and their effect on the tissue. Side effects of the radiation and the recovery. Introduction to cytostatic therapy at the departments as well as at the day clinic. Administration of cytostatics, side effects and recovery. How to take care of febrile neutropenia. Introduction to the biological therapy, administration, side effects and recovery
Ishodi učenja
Study outcome
Introducing students to breast-conserving and radical surgery performed on female patients. Anamnesis and status. Plan of the radiotherapy. Side effects and remedy of radiation. Administration of cytostatics. Premedication. Side effects and recovery of cytostatics. Exercise of rights to a wig or breast prosthetics.Lymph drainage.
Ishodi učenja
Study outcome
Cases of female patients with vaginal, vulva, uterus and ovaries tumors. Anamnesis and status.Brachytherapy- simulation of the application of radioactive caesium. Side effects and recovery
Ishodi učenja
Study outcome
Cases of patients with prostate tumors, localized illness and with metastazis. Anamnesis and status.Planning of conformal radiotherapy. Hormonal radiotherapy. Application of LHRH agonist. Radiation of bone metastasis. Cytostatic therapy in curing the prostate cancer.
Ishodi učenja
Study outcome
Cases of patients with intratoracal tumors: lungs tumors and mesotheliomas. Anamnesis and status. Planning of radical radiotherapy.Cytostatic and biological therapy. Getting the patient ready for the administration of cytostatics. Syndrome of vena cava and Pancoast syndrome, treated as emergencies in oncology
Ishodi učenja
Study outcome
Cases of patients with esophagus, stomach, pancreas and colorectal tumors. Radiation side effects and recovery. Cytostatic therapy for aforementioned tumors. Cytostatic side effects and recovery. Application of biological therapy. Anus praeter.
Ishodi učenja
Study outcome
Cases of patients with urinary bladder cancer and malignant kidneys tumors. Anamneses and status.Planning of radiotherapy concerning the urinary bladder cancer, immunotherapy. Biological therapy and its side effects. Recovery. Urostoma, nefrostoma
Ishodi učenja
Study outcome
Cases of patients with oral cavity, pharynx and larynx tumors. Anamnesis and status.Planning of concomitant chemoradiotherapy for the aforementioned tumors. Side effects and recovery from radiation and cytostatic therapy
Ishodi učenja
Study outcome
Cases of patients with malignant tumors of the central nervous system and paranasal sinuses. Anamnesis and status. Planning of radiotherapy for the glioblastoma and maxilla cancer. Therapy of the brain edema. Cytostatic therapy. Spinal cord compression. Supportive methods.
Ishodi učenja
Study outcome
Cases of patients with testicular tumor of seminoma and nonseminoma type. Anamnesis and status.Radiotherapy and cytostatic therapy. Side effects and recovery. Cryopreservation of sperm.
Ishodi učenja
Study outcome
Cases of basal cell carcinoma and planocellular skin carcinoma. Anamnesis and status.Radiotherapy. Treatment of radiodermatitis. Malignant melanoma. Treatment with special attention to biological therapy.
Ishodi učenja
Study outcome
Cases of bone and soft tissue tumors.Anamnesis and status. Treatment of sarcoma.
Ishodi učenja
Study outcome Cases of hematological malignant diseases. Anamnesis and status, Radiation of the lymphoma and plasmacytoma
Ishodi učenja
Study outcome
Cases of patients undertaking palliative treatment. Palliative patients’ diet. Gastrostomy PEG. Analgesic therapy. Pain clinic. Evacuation of ascites and pleural effusion.Palliative radiotherapy and chemotherapy.Teams for palliative care and hospices.