Nutrition, Metabolism, Aging, and Aging-related Diseases

Zavod za molekularnu medicinu i biotehnologiju

Classes held in English

Study programs

Medical Studies in English

Year of study

ISVU ID

292566

URL

ECTS

1.5

Incentive ECTS: 0 (0.00 %)

Lecturers

prof. dr. sc. Volarević Siniša, dr. med. coordinator

The course aims to introduce the students to the current understanding of the link between metabolism, cancer, and accelerated aging at the molecular level. Particular emphasis will be put on the role of unhealthy habits regarding eating and nutrition on cancer pathogenesis and accelerated aging. Students will also be informed about the implications of this knowledge for the prevention and treatment of aging-related diseases, particularly cancer and neurodegenerative disorders.

Lodish H, Berk A, Zipursky SL, Matsudaira P, Baltimore D, Darnell JE. (1999) Molecular Cell Biology. 4th edition, W H Freeman & Co.

Deleyto-Seldas N and Efeyan A. The mTOR-autophagy axis and the control of metabolism. Front Cell Dev Biol, 9:655731 (2021)

Vander Heiden MG et al. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science, 324:1029-1033 (2009)

de Cabo, and Mattson MP. Effects of Intermittent fasting on health, aging, and disease. N Engl J Med. 381:2541-2551 (2019)

Longo VD and Anderson RM. Nutrition, longevity, and disease: from molecular mechanisms to interventions. Cell. 185:1455-1470 (2022)

Classs attendance 70%.

1. Metabolic reprogramming in cancer

2. Dysregulation of energy metabolism in cancer

3. The key role of the insulin receptor-PI3K-mTORC1 signaling pathway in cancer and aging

4. Dysregulated protein synthesis drives cancer pathogenesis and accelerates aging

5. Unhealthy habits regarding eating and nutrition, metabolism, aging, and cancer

6. Healthy habits regarding eating and nutrition in cancer prevention and treatment

7. Healthy habits regarding eating and nutrition in slowing down the aging process

[Izvedbeni nastavni plan]

5 Metabolic reprogramming in cancer

This type of class is described in the syllabus, please contact the course coordinator for more details

4 Dysregulation of energy metabolism in cancer

2 The key role of the insulin receptor-PI3K-mTORC1 signaling pathway in cancer and aging

3 Dysregulated protein synthesis drives cancer pathogenesis and accelerates aging

3 Unhealthy habits regarding eating and nutrition, metabolism, aging, and cancer

4 Healthy habits regarding eating and nutrition in cancer prevention and treatment

4 Healthy habits regarding eating and nutrition in slowing down the aging process

This type of class is described in the syllabus, please contact the course coordinator for more details

Academic year
2025/2026	Preuzimanje

Course

Nutrition, Metabolism, Aging, and Aging-related Diseases

Study programs

Year of study

ISVU ID

URL

ECTS

1.5

Lecturers

Details 2025/2026

[Izvedbeni nastavni plan]

Learning outcomes

Learning outcomes

Learning outcomes

Learning outcomes

Learning outcomes

Learning outcomes

Learning outcomes