Course
Study programs
Medical Studies in EnglishYear of study
4ISVU ID
213822ECTS
8
“Infectious diseases and clinical microbiology” course comprises general matter: pathogenesis and etiology of infectious diseases, epidemiology of infectious diseases, clinical course of an infective disease and general signs and symptoms of an infectious disease as well as immune response to infective agent, diagnostic techniques used in infectious diseases and antimicrobial treatment. Specific matter in infectious diseases covers infectious diseases syndromes and infections of particular organic systems: respiratory tract infections, gastrointestinal infections, hepatobiliary tract infection, central nervous system infections, skin, bone, joint and soft tissue infections, urinary tract infections, bloodstream infections and sepsis. More, this course covers fever with rash, fever of unknown origin, zoonoses, and infections in immunocompromised patients and healthcare-associated infections. Protozaoal infections, infections with anaerobic bacteria, slow viral infections and other causative agents in infectious diseases are covered in this course. Separately, immunization and vaccines are emphasized as a key component of infectious disease burden control.
This course appends the matter of previous courses like internal medicine, physiology, pathophysiology, immunology, pharmacology, pathology and microbiology.
Lessons are organizes as lectures, seminars anf practical excercises wich mutually interfere and append and all forms of lessions are obligatory to master the course.
Seminars are integrated with seminars in clinical microbiology and present a learning unit. Microbiological part of the seminar covers pathogenesis of a particular infectious disease, virulence factors of pathogens and immune response pathways in order to resolve infection. Infectious diseases specialist guides second part of the seminar in order to present the clinical signs and symptoms of previously presented infectious disease, either in a bedside manner or as a case-report.
Students will be provided with all lectures synopses
Lectures will be held in main lecture room of The Clinical hospital center Rijeka and lecture room of Clinic for infectious diseases. Seminars will be held in a lecture room of Clinic for infectious diseases. Practical exercises will be performed in the Clinic for infectious diseases, Clinical hospital center Rijeka. All forms of lessions are obligatory, as regulated by Statue of the Faculty of Medicine in Rijeka.
Southwick FS. Infectious Diseases: Clinical Short Course, 4 th Ed. McGraw Hill Education, 2020.
Harrison´s Principles of Internal Medicine, 20th Ed. McGraw Hill Education, 2018.
Mandell, Douglas, and Bennett´s Principles and Practice of Infectious Diseases, 9th Ed. Churchill, Livingstone (Elsevier), 2020
Red book: 2021-2024 Report of the Committee on Infectious Diseases 32nd Ed. Itasca, IL, American Academy of Pediatrics, 2021.
All forms of classes are obligatory. Student has not fulfilled the requirements prescribed by the study programme, in case he/she was absent more than 30% of the course hours in all the course sections (lectures, seminars or practical work). These students must enroll again in the course in the next academic year. Student that has ≤30% of seminars or practical work default need to compensate the practical work in other time point or to pass the preliminary exam of the default seminar.
1. Students evaluations will be conducted according to the Ordinance on Student Grading at the faculty of Medicine in Rijeka
2. Total percentage of students´ success during the course constitutes up to 60% of the grade and 40% passing the final exam.
During the course student constitutes max. up to 60 % of the grade via 2 small exams formed as written essay. Each essay contains 30 questions from selected subjects that students answer in writing in period of 30 minutes. Small test essays will be conducted during the ordinary session and students can achieve up to 30% of grade on each.
3. Students who achieve ≥30 % of the overall grade from written essays can take final exam.
In the final exam the maximum is 40%.
- 35-40% Excellent (5)
- 30-34% Very good (4)
- 25-29% Good (3)
- 20-24% Sufficient (2)
Final exam is constituted from practical and oral part. Total credits at the final exam may be max. 40%.
Pass grades:
- 90-100% (5), A Excellent
- 75-89,9% (4), B Very good
- 60-74,9% (3), C Good
- 50-59,9% (2), D, Sufficient
- 0-49,9% (1), F Insufficient
Before taking the final exam student must present his Transcript of records signed by the Head of the course.
4. Student who has achieved ≤30 % of the final grade don´t have the right to take the final exam and must enroll again in the course in the next academic year.
5. All forms of classes are obligatory. Student has not fulfilled the requirements prescribed by the study programme, in case he/she was absent more than 30% of the course hours in all the course sections. These students must enroll again in the course in the next academic year.
6. Student that has ≤30 % of seminars or practical work default need to compensate the practical work in other time point or to pass the preliminary exam of the default seminar.
7. First exam essay includes principles of infectious diseases (Infectious diseases in general), Diagnostics and Therapy of infectious diseases and Infections of the Respiratory system. First exam essay will be held on March 16th 2026 at 08:00 am in the main lecture room of the Clinical hospital center Rijeka.
8. Second exam essay´s themes are Infections of the gastrointestinal system and Viral hepatitis, Infections of the Central nervous system, Sepsis and Skin and soft tissue infections. Second exam essay will be held on March 30th 2026 at 08:00 am in the lecture room of the Clinical hospital center Rijeka.
9. Repeat examination for one of exam essays will be held at single time point between two time dates of final exames for students who achieved ≤30 % of the final grade and those who were unable to attend exam essay due to illness. Repeat examination contains themes of the exam essay at which the student scored inferior result. Student can retake only ONE exam essay. Students who have achieved ≤30 % of the final grade after repeat examination don´t have the right to take the final exam and must enroll again in the course in the next academic year.
10. Final exam dates are 22.4.2026.; 26.06.2026., 10.07.2026., 08.09.2026. and 22.09.2026. The final exam results will be published on the web pages and on the notice board.
All changes in course programme and important informations regarding the Course will be announced on the web pages and on the notice board of the Department of infectous diseases placed in the atrium of the Clinic for infectious disease, Clinical Hospital Centre Rijeka. Time dates and hours for students consultations with lecturers, students personally arrange with the lecturer via e-mail or on site. Department´s officer Sanja Rivetti is available from Monday to Friday in period 8-12 am, contact phone number. +385 51 658 271; e-mail: infektologija@kbc-rijeka.hr
Learning outcomes
Learn the principles of infectious diseases: evolution and course of an infective disease, general and specific signs and symptoms of ID. Learn how to prevent an infectious disease (chemoprophylaxis, immunoprophylaxsis)
Learning outcomes
Learn the principles of antiinfective therapy, pharmacokynetics and pharmacodynamics of antimicrobial drugs, sidefects and interactions with other medications. Learn all groups of antibiotics and mechanisms of action. Learn indications for introduction of specific antibiotic and develop critical opinion about prescriptions of antibiotics.
Learning outcomes
Learn how to collect samples from a patient relevant for the diagnosis of an infectious disease, transport and storage of samples. Learn how to direct diagnostic procedures depending on presented signs and symptoms of ID and time passed from disease onset. Correlate laboratory analysis results with ID syndromes, know how to interprete results of serological or molecular analysis in order to establish the etiology of an ID
Learning outcomes
Learn about etiology, pathogenesis, epidemiology, clinical presentation, diagnostics, therapy, and prevention of respiratory infections. Learn how to differentiate and treat atypic and typic pneumonia. Learn about seasonal influenza and novel coronaviruses (SARS-CoV, MERS, SARS-CoV-2)
Learning outcomes
Learn about etiology, pathogenesis, epidemiology, clinical presentation, diagnostics, therapy (both supportive and antimicrobial), and prevention of GIT infections. Learn how to differentiate non-infective from infective diarrhea
Learning outcomes
Learn how to differentiate infective and non-infective hepatitis, understand the term „reactive hapatitis“. Learn which are the hepatotropic viruses, their etiology, epidemiology, pathogenesis, clinical presentation, diagnostics and treatment. Learn how to diagnose and treat chronic HBV and HCV hepatitis.Learn pre and post-exposure measurements od HBV infection. Learn how to prevent the spread of virusesthat cause virus hepatitis
Learning outcomes
Learn about etiology, epidemiology, pathogenesis, clinical course, diagnostics and treatment (antimicrobial and supportive) of CNS infections. Learn how to make clinical distinguish between infective meningitis and meningismus. Learn which antimicrobials to use in chemoprophylaxis of CNS infections.
Learning outcomes
Learn abouut etiology, clinical manifestations and treatment of skin and soft tissue infections. Learn about most frequent pathogens caousing skin and soft tissue infections and treatment approach.
Learning outcomes
Learn about etiology, epidemiology, pathogenesis and clinical presentation of sepsis and infectious endocarditis. Learn about the complications of unrecognized sepsis. Define the diagnostic and treatment approach to patinet with sepsis or infectious endocarditis. Learn the etiology and pathogenesis of toxic shock syndrome and the protocol for treatment of this disease.
Learning outcomes
Learn about etiology, epidemiology, pathogenesis, clinical course, diagnostics and treatment of infections with rash in pediatric population. Learn how to differentiate between different eflorescenses, learn about of the eflorescense distribution and evolution within the course of infections with rash
Learning outcomes
Learn about etiology, epidemiology, pathogenesis, clinical course and treatment of urinary tract infections; community- and intrahospital-acquired. Learn how to distinguish between asymptomatic bacteriuria and UTI.
Learning outcomes
Learn about the infectious mononucleosis syndrome and the most frequent etiology of IM. Learn how to establish the diagnosis of Fever of Unknown Origin and entities that cause FUO.
Learning outcomes
Learn about herpesviruses, epidemiology and clinical manifestations of infections caused by herpesviruses. Learn how to diagnose, treat and prevent single herpesvirus infection (from HHV-1 to HHV-8). Learn about coplications and long-term sequelae of herpesvirus infections.
Learning outcomes
Learn about epidemiology of zoonoses. Memorize most important zoonoses in human medicine (etiology, pathogenesis, clinical course and treatment). Learn about epidemics of individual zoonosis in Croatia
Learning outcomes
Learn about etiology, epidemiology, and pathogenesis. Clinical course, diagnosis and treatment ofsyphilism leptospirosis and Lyme disease.
Learning outcomes
Learn about global distribution of tropical diseases and importance of these diseases in terms of international travel and migrations. Learn about etiology, epidemiology, pathogenesis, clinical course and treatment of most frequent parasyte infections in Croatia
Learning outcomes
Learn the etiology, pathogenesis, clinical course and treatment of infections caused by anaerobic bacteria with emphasis on recognition of anaerobic infections within specific organ sysems. Learn about epidemiology, pathogenesis, clinical course, treatment and prevention of tetanus and botulism. Learn about pre- and post-exposure tetanus prophylaxis.
Learning outcomes
Learn about the infectious diseases caused by viruses that present with atypical clinical presenation and long incubation. Learn about the diagnostic and treatment approach ti patients with slow viral infections.
Learning outcomes
Learn the components of innate and adaptive immunity that interact with infectious pathogens and diseases that outcome from immunospupression (either genetic or therapy-induced). Learn about infections in splenectomized patients and modes of their prevention.
Learning outcomes
Learn about the mechanisms of immunoprophylaxis. Memorize official immunization schedule in Croatia. Learn about vaccination in special circumstances.
Learning outcomes
Learn how to take anamnesis from a patient, including epidemiological data, which can point to final diagnosis. Learn how to perform complete physical exam of a patient with an infectious disease, how to examine meningeal signs, how to perform full oral cavity exam and detailed skin exam
Learning outcomes
Learn the specificities of pediatric anamnesis (course of pregnancy and delivery, early childhood development, vaccination status). Learn how to perform physical exam in a child.
Learning outcomes
Learn how to perform oral cavity examination and how to collect oropharyngeal and nasopharyngeal swab sample. Based on oral cavity examination status learn how to differentiate between viral and bacterial pharyngitis, and herpangina from herpesvirus stomatitis. Learn how to properly diagnose BHS-A pharyngitis, how to differentiate between colonization and infection. Learn how to properly interpret the results form microbiology analysis of OF / NF swab sample.
Learning outcomes
Learn how to peform neurological status of a patient with emphasis on meningeal signs. Identify specific clinical signs and symptoms of central nervous system infection. See the process of proper preparation and performance of lumbal puncture. Learn how to properly interpret the results of cell-, biochemicaland microbiological- analysis of cerebrospinal fluid. Learn the etiology and clinical course of aseptic and bacterial meningitis
Learning outcomes
Learn how to perform physical examination of chest with emphasis on auscultation of heartbeats and respiratory phenomena. Establish clinical diagnosis of respiratory tract infection and suggest appropriate biochemical and haematology analysis. Learn to recognize specific alterations in chest X-ray that indicate pneumonia. Learn how to properly perform epidemiological anamnesys in patients with respiratory system infections.
Learning outcomes
Learn which are the clnical syndromes that urge obtaining blood culture samples. Learn how to adequately obtain and process blood cultures in oder to avoid false positive results. Learn proper interpretation of the blood cultures results in accordance to blood analysis (levels of inflammatory response). Learn how to diagnose infective endocarditis (Duke´s cryteria) and know the most common agents that cause iE
Learning outcomes
Learn how to discriminate between clinical sydromes enteritis, colitis, gastroenteritis, enterocolitis and gastroenterocolitis according to presented symptoms of the syndrome. Learn how to interpret the results of stools macro- and mycroscopic analysis in accordance to etiology of diarrhea (bacteria / virus /parasytes / fungi). Learn which non-infective syndroms are included in differential diagnosis of acute diarrheal syndrome. Learn the basis of supportive therapy of acute diarrhea and is in when is appropriate to introduce antibiotics in therapy
Learning outcomes
Learn the symptoms of hepatobiliary tract infections. Learn how to interpret results of hepatogramme and serology tests in virus hepatitis. Know which syndromes are included in differential diagnosis of icterus. Learn about epidemiology and prevention of viral hepatitis
Learning outcomes
Learn how to perform the examination of liymph nodes in patients. Know how to interpret the results of cytology analysis of lymph nodes. Learn the differential diagnosis of lymphadenitis
Learning outcomes
Learn how to proprerly obtain urin sample for microbiological analysis. Learn how to obtain prostate exprimate nad uretral swab. Learn proper interpretation of microbiological and cytological urine analysis results. Know how to differentiate between different clinical syndromes of urinary tract infection based on presented symptoms of the disease.
Learning outcomes
Learn the pathogenesis models of infectious diseases and principles of pathogen proof. Learn how to extract human samples for microbiological analysis. Learn how to properly transport or store samples in order to perform analysis. Define the changes in biochemical and hematology values depending on the etiology of infectious disease. Discriminate between molecular and serology tests used to diagnose infectious pathogens. Learn how to interpret results of bacterial cultures and related antibiogram.
Learning outcomes
Learn the pathogenesis models of infectious diseases and principles of pathogen proof. Learn how to extract human samples for microbiological analysis. Learn how to properly transport or store samples in order to perform analysis. Define the changes in biochemical and hematology values depending on the etiology of infectious disease. Discriminate between molecular and serology tests used to diagnose infectious pathogens. Learn how to interpret results of bacterial cultures and related antibiogram.
Learning outcomes
Learn etiology, epidemiology, pathogenesis, clinical course, diagnostics and treatment of respiratory infections. Learn how to differentiate between typical and atypical pneumonia based on patients´ anamnesis, radiological scans and hematology and biochemical values. Differentiate flu and cold. Learn abot the complications of the flu
Learning outcomes
Learn etiology, epidemiology, pathogenesis, clinical course, diagnostics and treatment of respiratory infections. Learn how to differentiate between typical and atypical pneumonia based on patients´ anamnesis, radiological scans and hematology and biochemical values. Differentiate flu and cold. Learn abot the complications of the flu.
Learning outcomes
Learn epidemiology and pathogenesis of gastrointestinal infections; differentiate between infectious and non-infectious causes of diarrhea. Learn te principles of epidemiology anamnesis in patients with gastrointestinal infection; discriminate between viral and bacterial pathogens as possible cause of infectious diarrhea based on biochemical and hematologic values in blood of infected patients. Leran how to diagnose, differentiate the stage of and treat dehydration. Determine proper diet in patients with gastrointestinal infection
Learning outcomes
Learn epidemiology and pathogenesis of gastrointestinal infections; differentiate between infectious and non-infectious causes of diarrhea. Learn te principles of epidemiology anamnesis in patients with gastrointestinal infection; discriminate between viral and bacterial pathogens as possible cause of infectious diarrhea based on biochemical and hematologic values in blood of infected patients. Leran how to diagnose, differentiate the stage of and treat dehydration. Determine proper diet in patients with gastrointestinal infection
Learning outcomes
Learn the etiology of acute hepatitis. Recognize tipical changes in biochemical values in blood of patients with hepatitis. Learn how to diagnose viral hepatitis usin serologic and molecular methods. Learn how to prevent viral hepatitis. Interpret the results of hepatobiliary ultrasound analysis. Differentiate between infectious and non-infectious hepatitidies.
Learning outcomes
Learn the etiology of acute hepatitis. Recognize tipical changes in biochemical values in blood of patients with hepatitis. Learn how to diagnose viral hepatitis usin serologic and molecular methods. Learn how to prevent viral hepatitis. Interpret the results of hepatobiliary ultrasound analysis. Differentiate between infectious and non-infectious hepatitidies.
Learning outcomes
Learn to differentiate age-related etiology of bacterial meningitis. Learn about the pathogenesis of CNS infections. Differentiate between para- and post-infective encephalitis. Recognize characteristic physical signs of meningitis. Learn empiric therapy of bacterial meningitis. Defferentiate between meningismus and meningitis. Learn how to interpret results of cerebrospinal fluid cytologic and biochemical analysis.
Learning outcomes
Learn to differentiate age-related etiology of bacterial meningitis. Learn about the pathogenesis of CNS infections. Differentiate between para- and post-infective encephalitis. Recognize characteristic physical signs of meningitis. Learn empiric therapy of bacterial meningitis. Defferentiate between meningismus and meningitis. Learn how to interpret results of cerebrospinal fluid cytologic and biochemical analysis.
Learning outcomes
Learn the etiology, pathogenesis, clinical and clinical course of most frequent infections of the skeletal system. Learn about the diagnostic tools appropriate for diagnosis of skeletal system infections. Learn differential diagnosis of “back pain”. Learn how to interpret biochemical and hematology results in the diagnostic process of sceletal system infections.
Learning outcomes
Learn the etiology, pathogenesis, clinical and clinical course of most frequent infections of the skeletal system. Learn about the diagnostic tools appropriate for diagnosis of skeletal system infections. Learn differential diagnosis of “back pain”. Learn how to interpret biochemical and hematology results in the diagnostic process of sceletal system infections.
Learning outcomes
Learn the etiology of bacteraemia and sepsis, clinical presentation of sepsis, diagnostics and treatment protocols. Learn about infectious mononucleosis syndrome.
Learning outcomes
Learn the etiology of bacteraemia and sepsis, clinical presentation of sepsis, diagnostics and treatment protocols. Learn about infectious mononucleosis syndrome.
Learning outcomes
Learn the etiology of community-acquired UTI, clinical course, diagnostics and treatment protocols. Learn how to interpret results of cyto- and biochemical urine analysis and microbiological urine cultures with associated antibiograms. Learn the etiology, pathogenesis, clinical course and treatment of STDs. Learn prophylactic protocols for STDs
Learning outcomes
Learn the etiology of community-acquired UTI, clinical course, diagnostics and treatment protocols. Learn how to interpret results of cyto- and biochemical urine analysis and microbiological urine cultures with associated antibiograms. Learn the etiology, pathogenesis, clinical course and treatment of STDs. Learn prophylactic protocols for STDs.
Learning outcomes
Learn the etiology, pathogenesis, diagnosis and treatment of congenital (TORCH) nad neonatal infections. Learn how to perform prenatal serological screening in pregnant women in order to prevent congenital and neonatal infections
Learning outcomes
Learn the etiology, pathogenesis, diagnosis and treatment of congenital (TORCH) nad neonatal infections. Learn how to perform prenatal serological screening in pregnant women in order to prevent congenital and neonatal infections.
Learning outcomes
Know the most frequent etiological agents of HAI. Learn the protocols of HAI prevention and management. Learn about the measures of detecting and follow up of bacterial antimicrobial resistance in Croatia. Understand the mechanisms of antimicrobial resistance in specific pathogens (MRSA, ESBL+ microorganisms, VRE etc.)
Learning outcomes
Know the most frequent etiological agents of HAI. Learn the protocols of HAI prevention and management. Learn about the measures of detecting and follow up of bacterial antimicrobial resistance in Croatia. Understand the mechanisms of antimicrobial resistance in specific pathogens (MRSA, ESBL+ microorganisms, VRE etc.)
| Academic year | |
|---|---|
| 2025/2026 | Preuzimanje |